Courtesy of The Joint Blog
For the study, researchers used synthetic cannabinoids (natural, cannabis-derived cannabinoids are typically even more effective) on mice with skin cancer in a 20 week study, and found that the cannabinoids had a hugely positive effect, reducing skin cancer by up to 90% as well as “inhibiting tumor promotion”.
This is the first report indicating the structure-activity relationships for the anti-inflammatory activity of synthetic cannabinoids on TPA-induced inflammation in mice. Naphthoylindoles, JWH-018, -122 and -210 [synthetic cannabinoids], had the most potent anti-inflammatory activity and also markedly inhibited tumour promotion by TPA in the two-stage mouse skin carcinogenesis model. The present results suggest that synthetic cannabinoids, such as JWH-018, -122 and -210, may be used as cancer chemopreventive agents in the future.